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Lexapro is manufactured by Forest Pharmaceuticals, Inc. Neurotransmitters carry signals from one nerve cell to another.Research suggests that abnormalities in neurotransmitter activity can affect mood and behavior.Also, SSRIs have very different molecular structures. Zoloft (Sertraline hydrochloride) was the second SSRI to come to market in the United States, and it was approved by the FDA in December 30, 1991. Paxil (Paroxetine hydrochloride) was the third SSRI to come to market in the United States and was approved by the FDA in December 29, 1992. Chemical structure of Paroxetine differs from other SSRIs by having a piperidine ring.The first drug in the SSRI class was Prozac (Fluoxetine), which hit the United States market in 1987. Luvox (Fluvoxamine maleate) was the next SSRI FDA approved in December 05, 1994.To restore access and understand how to better interact with our site to avoid this in the future, please have your system administrator contact [email protected], antihistamine, and anticholinergic effects. The drug is not considered a first-line treatment for depression since the introduction of selective serotonin reuptake inhibitor (SSRI) antidepressants, which have fewer side effects and are safer in overdose.

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The drug reduced anxiety and increased life quality.

However, now its marketing status is "Discontinued".

Celexa (Citalopram hydrobromide) was approved by the FDA in July 17, 1998.

Based on "Essential Psychopharmacology" written by Stephen M.

Stahl, MD, Ph D by e Med Expert staff Medical references reviewed: August, 2018 The most significant class of antidepressants marketed in recent years is the selective serotonin reuptake inhibitors (SSRIs).

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